Receptor-mediated endocytosis in steroid hormone-producing tissue.

نویسندگان

  • K E Suckling
  • B Ochoa
چکیده

Dietschy, J. M., Kita, T., Suckling, K. E., Goldstein, J. L. & Brown, M. S . (1983) J . Lipid Res. 24, 469-480 Edge, S. B., Hoeg, J. M., Triche, T., Schneider, P. D. & Brewer, H. B. (1986) J . B i d . Chem. 261, 38063806 Ford, R. P.. Botham, K. M., Suckling, K. E. & Boyd, G. S. (1985) FEBS Lert. 179, 177-180 Halloran, L. G., Schwartz, C. C., Vlahcevic, Z. R., Nisman, R. M. & Swell, L. (1978) Surgery 84, 1L7 Harkes, L. & van Berkel, T. J. C . (1984) Biochim. Biophys Acra 794, 340 -347 Herold, G.. Schneider, A,, Ditschuneit, H. & Stange, E. F. (1984) Biochim. Biophys. Actu 796. 2 7 3 3 Hoeg, J . M., Demosky, S. J., J r . , Schaefer, E. J., Starzl. T. E. & Brewer, H. B.. Jr. (1984) J . Clin. Invest. 73, 429-436 Kagami, A,, Fidge, N., Suzuki, N. & Nestel, P. (1984) Biochim. Biophys. Ac/u 795, 179-190 Lippiello, P. M., Sisson, P. J. & Waite, M. (1985) Biochem. J . 232, 395~40 I Mitropoulos, K. A,, Myant, N. B., Gibbons, G. F., Balasubramaniam, S. & Reeves, B. E. A. (1974) J. Biol. Chem. 249, 6052-6056 Nervi, F., Bronfman, M., Allalbn, W., Depiereux, E. & Del Pozo, R. (1984) J . Clin. Invest. 74, 2226-2237 Normann, P. T. & Norum, K. R. (1976) Scand. J . Gastroenrerol. 11, 427432 Robins. S. J., Fasulo, J. M., Collins, M. A. & Patton, G. M. (1985) J . Biol. Chem. 260, 651 1-6513 Schwartz, C. C., Vlahcevic, Z. R., Halloran, L. G., Gregory, D. H., Meek, J . B. & Swell, L. (1975) Gastroenterology 69, 1379-1382 Schwartz. C. C., Vlahcevic, Z. K., Halloran, L. G., Nisman, R. & Swell, L. (1977) Proc. Soc. Exp. Biol. Med. 156, 261-264 Schwartz, C. C., Halloran, L. G., Vlahcevic, Z. R., Gregory, D. H. & Swell, L. (1978~) Science 200, 62-64 Schwartz, C. C., Berman. M., Vlahcevic, Z. R., Halloran, L. G., Gregory. D. H. & Swell. L. (19786) J . Clin. Invest. 61, 408-423 Singer, I . I . , Kawka, D. W., Kazazis, D. M., Alberts, A. W., Chen, J . S.. Huff, J. W. & Ness, G. C . (1984) Proc. Narl. Acad. Sci. U.S.A. 81. 5556-5560 Sodhi, H. S., Orchard, R. C., Agnish, N. D., Varughese. P. V. &

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).

Steroid hormones are central regulators of a variety of biological processes. According to the free hormone hypothesis, steroids enter target cells by passive diffusion. However, recently we demonstrated that 25(OH) vitamin D(3) complexed to its plasma carrier, the vitamin D-binding protein, enters renal proximal tubules by receptor-mediated endocytosis. Knockout mice lacking the endocytic rece...

متن کامل

Cellular uptake of steroid carrier proteins--mechanisms and implications.

Steroid hormones are believed to enter cells solely by free diffusion through the plasma membrane. However, recent studies suggest the existence of cellular uptake pathways for carrier-bound steroids. Similar to the clearance of cholesterol via lipoproteins, these pathways involve the recognition of carrier proteins by endocytic receptors on the surface of target cells, followed by internalizat...

متن کامل

Prognostic Values of Estrogen and Progesterone Expression Receptors in Ovarian Papillary Serous Carcinoma

  Background and Objectives: Presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. Since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic value of the estrogen receptor (ER) and progesterone receptors (PR) in ovarian papillary ser...

متن کامل

The LDL receptor and the regulation of cellular cholesterol metabolism.

I N T R O D U C T I O N Cholesterol is a structural component of the plasma membrane that surrounds animal cells. It is absolutely essential for cell growth and survival. Yet, excessive amounts of cholesterol can also be lethal as when massive amounts of cholesterol deposit in cells of the artery wall producing atherosclerosis. Thus, animal cells have evolved a highly ordered mechanism for regu...

متن کامل

Correlation of Hormone Receptor Expression with Histologic Parameters in Benign and Malignant Breast Tumors

Background and Objective: Breast cancer is the commonest cancer of Indian women. Estrogen and Progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. Although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...

متن کامل

“Bound” to Work: The Free Hormone Hypothesis Revisited

Megalin is a member of the low-density lipoprotein receptor-related protein (LRP) family. The plasma membrane-anchored LRPs serve as receptors for a wide variety of extracellular ligands, promoting their entry into cells by endocytosis of the receptor-ligand complex. In this issue of Cell, Hammes et al. (2005) show that resistance (insensitivity) to sex steroid hormones is encountered in animal...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Biochemical Society transactions

دوره 15 2  شماره 

صفحات  -

تاریخ انتشار 1987